Comparative Study of Different doses of Thiopentone Soudium in Donkeys (Equusafricanus)

Abstract

The purpose of this study was to report the quantitive and qualitative aspects of intravenous anesthesia using thiopentone sodium in donkeys under field conditions.In these study ,two different dose of thiopentone were evaluated as follow: donkeys in two groups of animals each on composed of four animals . group one anesthesied by thiopentone soudium at the dose rate 7 mg /kg body weight and group two given 12mg/kg body weight . physiological paramrters(Heart rate,respiratory rate, and rectal temperature) were manitored before and after the induction at 10 minutes interval until one hour. Anaesthetic phases (induction, duration of anaesthesia,lateral recumbency, sternal recumbency and recovery) and some anesthetic reflexes were measured and recoded post induction and throughout the duration of anaesthesia. The two tested doses of thiopentone sodium produced satisfactory induction, good muscle relaxation , quite smooth recovery. The increased dose of thiopentone sodium from 7 to 12 mg/kg resulted in no significant increase in induction time (P>0.05) and significant (P < 0.05) increase in the duration of anaesthetic phase and recovery phase. The use of thiopentone sodium in both doses tested were accompanied by significant increase (P < 0.05) in heart rates, while rectal temperature showed significant fluctuation. Animals treated with both protocols showed significant decrease(P < 0.05) in respiratory rate immediately following induction of anaesthesia. In conclusion, this simple anaeshetic doses can be used to induce acceptable anaesthesia as well as areasonable expected recovery. Key words: Anaesthesia , donkeys , Sodium thiopentone.