Measurement of Some Coagulation parameters among Sudanese Pregnant Women in Police Hospital – Khartoum Sudan

Abstract

This is a cross-sectional descriptive and analytical study was conducted in police Hospital during the period from March to June 2013. The aim of this study to assess the haemostatic parameters (prothrombin time (PT), activated partial thromboplastine time (APTT) and Fibrinogen Level in healthy Sudanese pregnant women who attended police hospital (obstetric ward). Ninety samples (90) were collected from Sudanese women (60 pregnant women and thirty non pregnant women as control). The participants were informed about the study and agreed for participation. The study population was divided into three groups according to stage of pregnancy: First, second and third trimester. 1.8 ml of venous blood were collected from each subject in tri sodium citrate containers. These samples were tested for PT, APTT and fibrinogen level. Coagulometer (Biosystem) was used for the estimation of the coagulation profile (PT, APTT and fibrinogen level). Statistical analysis showed significant decrease in PT and APTT (p.value <0.05) . The study was also showed that there was a significant increase in plasma fibrinogen level in pregnant women when compared with non pregnant women with p.value (<0.05).