Cytological Change in Buccal Mucosa among Chronic Cigarette Smokers

Abstract

This study was carried out in WD hammed village River Nil State Sudan to assess the effect of smoking cigarettes on oral mucosal. The studies have carried out during the period from May to December 2012, the study included 100male cigarette smokers and 50 non smoker the average of ages was 50 years. The samples were collected from bucal mucosa, and stained by two methods Pap stain and Diff quick. Epithelial dyskaryosis was detected in four (4%) of the 100 studied subjects, it also shows that an Infection detect in nineteen (19%) of the smoker in the different age group, show heavy neutrophils infiltration in the buccal smear indicated infection. Only two individual in control group (51-70years old) had relatively mild neutrophils infiltration. Dyskaryosis was seen in buccal smear of four older smokers (51-70years) who smoked more than 31years. Three of those smoked 16-20 cigarettes daily . Smoking may be regarded as a risk factor developing oral epithelial dyskariotic, therefore it is better to users of cigarettes subject to periodic inspection. Oral Exfoliative cytology is reliable, simple and non invasive procedure that can be implemented for comprehensive oral screening program. Pap stain was preferred to diff quick because it stains nuclei very clearly. ‫.‪Further studies covering large sample size is recommended‬‬