Investigation of phytochemicals from some Sudanese Medicinal Plants and their Antimicrobial potency

Abstract

The present study was designed to investigate the antioxidant and antimicrobial activities of three Sudanese plants ; (Rheumpalmatum Rutagraveolens, Moringaperegrine) Phyto chemical study was conducted to detect thebioactive compounds. The crude ethanolic extract was partitioned successively by chloroform , ethyl acetate and n-butanol. Different fractoins were assessed for antimicrobial potency against standard bacterial strains: Gram positive ( Bacillus subtilis (NCTC8236), Staphylococcus aureus (ATCC25923); Gram negative ( Escherichia coli -ATCC25922, Pseudomonas aeruginosa -ATCC27853 ) and the fungal species : Candida albicans (ATCC7596). The cup-plate agar diffusion method was used. The antioxidant activities were conducted via DPPH radical scavenging assay. The results of phytochemical screening showed that all extracts contain flavonoids, saponins, triterpenes, steroids and tannins. This study demonstrated antioxidant and antimicrobial properties for the studied species, and showed interesting correlation between phytochemical constituents and biological activities