Frequency of Red Blood Cells Allo-Antibodies Among Sudanese Multi- Parous Women in Khartoum State

Abstract

This study was carried out in Khartoum State during the period from April-2012 to May-2012 to test allo-immunization against red blood cells among Sudanese multi-parous women. The aim of this study was to detect the frequency and type of allo-antibodies in randomly selected 80 pregnant women; all of them were attending Al-Turki Teaching Hospital during this period. Blood Samples were collected from pregnant women. Each sample was ABO Rh (D) grouped and screened for allo-antibodies, then samples that gave positive antibody screening were tested for antibody identification using gel agglutination method. Red cell allo-antibodies were found in 8 cases (10%). The identified antibodies 2(25.0%), anti-Cw 1(12.5%). Also were anti-Kell 1(12.5%), the results anti-S was 3(37.5%), 1(12.5%) revealed that, and no anti- E anti-Lea significant relationship was found between age and presence of allo- antibodies with P value (0.097). Also insignificant relationship was found between history of red cell transfusion and allo-immunization with P value (0.556), thus may be for the small number of tested women. A significant relationship was observed between history of abortion, number of pregnancies and presence of allo-antibodies with a P values (0.027, 0.002) respectively.‫‪This study recommended that the importance of performing‬‬ ‫‪and identification in our blood banks in‬‬ ‫‪antibody screening‬‬ ‫.‪Sudan for all pregnant women‬‬