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https://repository.sustech.edu/handle/123456789/17636| Title: | DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF GLIBENCLAMIDE |
| Other Titles: | تطویر واعتماد طریقة مطیافیه لتقدیر الجلایبینكلاماید |
| Authors: | Salih, Randa Salah Ahmed Supervisor, - Alfateh Ahmed Hassan |
| Keywords: | Chemistry ESTIMATION OF GLIBENCLAMIDE DEVELOPMENT AND VALIDATION UV SPECTROPHOTOMETRIC |
| Issue Date: | 10-Dec-2016 |
| Publisher: | Sudan University of Science and Technology |
| Citation: | Salih, Randa Salah Ahmed . DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF GLIBENCLAMIDE / Randa Salah Ahmed Salih ; Alfateh Ahmed Hassan .- Khartoum: Sudan University of Science and Technology, college of Science, 2016 .- 59p. :ill. ;28cm .- M.SC. |
| Abstract: | A simple, selective, linear, precise and accurate UV-VIS method was developed and validated for rapid assay of glibenclamide in pharmaceutical dosage forms. The validation parameter such as (linearity, precision, accuracy detection limit, quantitation limit) was validated according to the international conference of Harmonization. In the linearity the regression equation found to be Y= 0.0575X with a correlation coefficient R2 =09996 Statistical data reveals the method is accurate, selective and precise for the quantitation of Glibenclamide. The method was successfully applied for the routine analysis of Glibenclamide in tablet dosage. |
| Description: | Thesis |
| URI: | http://repository.sustech.edu/handle/123456789/17636 |
| Appears in Collections: | Masters Dissertations : Science |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| DEVELOPMENT AND VALIDATION....pdf | Research | 880.81 kB | Adobe PDF | View/Open |
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