Measurement of Complete Heamogram, Prothrombin Time and Active Partial Thromboplastin Time in Sudanese Cigarette Smokers

Abstract

‫‪This was Descriptive cross sectional study and analytical study‬‬ ‫.2102 ‪conducted at Omdurman Hospital during the period March to August‬‬ ‫,)‪The aim of this study is to estimate complete blood cell count (CBC‬‬ ‫‪prothrombin time (PT) and activate partial thromboplastin time (PTT) in‬‬ ‫.‪Sudanese cigarette smokers‬‬ ‫-‪45 samples from cigarette smokers and 30 health individual non‬‬ ‫‪smokers were withdrawn and participants were informed about the study and‬‬ ‫‪agreed for participation. The study population was divided into three groups‬‬ according to duration of smoking. Venous blood of 5ml was bleed (2.5ml in EDTA containers and 2.5ml in trisodium citrate container and investigated for the count of erythrocyte, white blood cell (WBC) and hemoglobin in full automated hematology analyzer (Sysmex) was used for the (CBC) analysis and manual analysis for prothrombin time(PT) and partial thromboplastine time(PTT). All cigarette smokers had mean values of hemoglobin (Hb) of 15.1 +_ 1.5g/dl), total white blood cell of 6.4x109 /L, erythrocyte RBC of 5.2 million/ mm3 ), prothrombitime (PT) of 14.4 second and partial thromboplastine (PTT) of 25.6 second platelets 241x109 /L. The results of this study concluded that erythrocyte count and Hb were significantly increased in smokers (p<0.000) but platelets and partial thromboplastin time were significantly decreased in smokers (p<0.05). The result also indicated that total white blood cell (WBC) and prothrombin time (PT) were normal in smokers. Packet cell velum PCV and mean cell hemoglobin were significantly increase (p<0.000) in smokers