Assessment of renal function during various trimesters of pregnancy in healthy Sudanese women

Abstract

An analytical study conducted during the period from March to July 2012, compared plasma levels of urea, creatinine, uric acid and albumin of 80 apparently healthy pregnant women (as a test group) and 40 apparently healthy (non-pregnant) volunteers (as a control group), to find if there is any changes in the plasma levels of urea, creatinine, uric acid and albumin in apparently healthy Sudanese women during pregnancy. All participants in this study were from Khartoum state (The test group and the control group were matched for age). The plasma levels of urea, creatinine, uric acid and albumin were measured using a colorimeter and commercial kits from CRESCENT, VITRO and SPINREACT Companies. The means of the plasma levels of urea and creatinine were found to be significantly reduced in the test group in all trimesters when compared to the control group while albumin and uric acid has insignificant reduced from control group. The plasma levels of urea, Creatinine, uric acid and albumin have no correlation with the duration of pregnancy. ‫,‪In conclusion, the plasma levels of urea‬‬ ‫‪Creatinine, uric acid and albumin are reduced‬‬ ‫‪during pregnancy. Plasma urea, creatinine, uric‬‬ ‫‪acid and albumin have no correlation with the‬‬ ‫.‪duration of pregnancy‬‬