STUDY OF THE ASSOCIATION OF THYROID FUNCTION WITH HEART DISEASE

Abstract

This study was conducted to study whether there is a relationship between the variation of the serum thyroid hormone levels (TSH, FT3 and FT4) and the presence heart disease. The study was done at Sudan cardiac Center and Radioimmunoassay laboratory of Khartoum (RICK) at the nuclear medicine department and medical laboratory (January 2016 to August 2016). A total of 50 patients their average age was 55.9 selected from Echocardiography patients and then followed persons prospectively to assess measured thyroid function Data collected included information of Echocardiography report and results of TFT and Lipid profile, reviewers independently abstracted and assessed studies. The results of this study revealed that when thyroid hormones (T3) increase the heart beating increase, relation between the two variable (EF, T3),with the maximum hormone level between 1&3 T3 ml/dl , and 40% EF starting point and 75% ending point. When thyroid hormones (TSH) decrease the heart beating decrease, ( EF ,TSH),with the maximum hormone level between 0.78 & 1 T3 ml/dl ,and 78% EF starting point and 60% ending point , when thyroid hormones (TSH) decrease the heart beating decrease, (T3, TSH),with the maximum hormone level between 0.4 &1 TSH ml/dl and 2 T3 ml/dl starting point and 1.80 T3 ml/dl ending point, when thyroid hormones (TSH) decrease the heart beating decrease, (T4, TSH),with the maximum hormone level between 0.3 & 3 TSH ml/dl and 150 T4 ml/dl starting point and 3 T4 ml/dl ending point. It concluded that thyroid hormones exerts multiple effects on the heart and vascular system.