Evaluation of Technetium 99m-DTPA and Excretion Urography in Renal Disorders

Abstract

Despite the advances in radiologic techniques, no criterion standard exists for the noninvasive imaging evaluation of the urinary collecting system, with each modality having its own set of pitfalls that preclude optimal visualization of the entirety of the urinary system. Excretory urography has been used in general to assess the integrity of the urinary tract status. Also renal scintigraphy has been used for a long time to measure the relative renal function; where different radiopharmaceuticals such as Tc-99m DTPA were used. In this essence the main objective of this study was to evaluate the renal function using excretion urography (EU) and renal scintigraphy. This study consisted of 100 patients suffering from renal disorders; all patients underwent excretion uorography and renal scintigraphy 99mTc-DTPA. The result of this study revealed that Tc-99m DTPA showed the same sensitivity as EU which is = 100% but Tc-99m DTPA has been accomplished in a shorter time (20 mints) in respect to EU (24 hours) for nonfunctioning kidney as well as patient will receive a substantial amount of radiation dose in EU. In conclusion in EU the amount of radiation to the patient increase in respect to the patient age; where exposure factor Kv and mAs increase linearly with the patient age in addition to the delayed film (nonfunctioning kidney) which results in more exposure, where entrance-surface air kerma also increases directly by 0.3 unit per each one Kvp and mAs.