Characterization of Corpus Callosum in Sudanese Population using Magnetic Resonance Imaging

Abstract

Corpus callosum is vital part of the human brain because it enhances and maintains communication between brain hemispheres. It is likely to be affected by the physiologic, as well as pathological changes occurred in the regions of brain. Also corpus callosum dimensions and texture might be change in respect to age which generally might insinuate or simulate pathology. Therefore Study of normal measurements of corpus callosum is helpful in providing baseline data for recognizing and diagnosing the presence and progression of diseases as well as to differentiate between degenerative changes and pathological changes. The aim of this work was to provide a Sudanese index (dimension) for corpus callosum and the associated parts in the normal people and the changes in the measurement that attributed to ageing and compare it with the published data. A number of MRI scans of 50 adult patients (male and female) aged between 10 – 74 years, having no brain disorders that affect the corpus callosum, were collected from department of radiology at Modern Medical Center Alzaytouna Hospital, and Royal Care International Hospital. The results showed that the average genu, trunk and selenium widths are 11.63 +/- 1.77, 6.04+/- 1.18 and 11.37 +/- 1.85 mm respectively. The study concluded that according to the normal cells adaptation the age have direct effect on the corpus callosum size and noted that increase in age lead to decrease in corpus callosum dimensions