Evaluation of Hematological Parameters and Iron Status among Chronic Renal Failure Patients Attending Sudanese Kidney Transplantation Association Hospital

Abstract

This is a hospital based analytical descriptive cross sectional case-control study was conducted in Kidney Transplantation Association Hospital during period from 2 April 2012 to 10 May 2012 to determine the morphological patterns of anemia an iron status among chronic renal failure patients attending Kidney Transplantation Association Hospital. Blood samples were collected under sterile condition from seventy patients with chronic renal failure as case group and thirty from healthy individuals as control group. The hematological parameters, serum iron and serum ferritin were measured using automated hematological analyzer machine (Sysmex KX 21) and (selectra XL). Data obtained were analyzed using soft ware program Statistical Package of Social Science (SPSS version 11.5). that the means The results showed of hemoglobin (8.5 g/dl), hematocrit ( 26.7%) and RBCs count (3.0×106 /μl) of case group were statistically significant low. The frequency and percent study showed that the of anemia among case group were anemic 69 (98.5%) mean Hb(8.4 g/dl) and remaining one case was non anemic with hemoglobin mean (12.0 g/dl). Also found the type of anemia among chronic renal failure patients was normocytic normochromic anemia 65(94.2%). The study showed that there was statistically significant decrease (P<0.05) in the level of serum renal failure patients with the mean iron in chronic ( 63μg/dl) when compared to the mean of control group with mean (96μg/dl).‫‪The study showed that there was statistically significant‬‬ ‫‪chronic‬‬ ‫‪in‬‬ ‫‪ferritin‬‬ ‫‪increase(P<0.05) in the level of serum‬‬ ‫‪mean (581μg/l) when‬‬ ‫‪the‬‬ ‫‪with‬‬ ‫‪patients‬‬ ‫‪failure‬‬ ‫‪renal‬‬ ‫.)‪compared to the mean of control group with mean(72 μg/l‬‬