Sputum Cytomorphology among Sudanese Patients Infected with Pulmonary Tuberculosis Attending Alshaab and Tropical Diseases Teaching Hospitals

Abstract

This is a hospital- based cross sectional study conducted at Khartoum state during the period of March to August- 2012 aimed at determining the cytomorphological pattern in the sputum smears of pulmonary tuberculosis infected Sudanese patients attending Alshaab and Tropical Diseases Teaching Hospitals . One hundred and fifty patients were included in this study, of which hundred patients (66.7%) were infected with pulmonary tuberculosis (+ve Zn stain) considered as study group and fifty patients (33.3%) were free from infection (-ve Zn stain) considered as control group. Fifty three of the patients were male, the remaining forty seven were female. Forty six patients were with age ranged between 33-53 years old. Asputum sample was collected from each patient, smeared, fixed and stained with MGG stain. Sixty two of the patients smears showed a features of chronic inflammation(lymphocytes,macrophages along with necrotic material at the background), twenty four showed features of acute inflammation(polymorph nuclear leukocytes) and only four patients appeared with normal cytological finding.Thirty six of control samples appeared with normal cytological features, tenwith acute inflammation and only four chronic inflammatory changes.‫‪relation between cytological pattern and alcohol‬‬ ‫‪No significant‬‬ ‫.)2.0 ‪abusing (P value‬‬ ‫.)6.0 ‪No relation between gender and cytological pattern (P value‬‬ ‫‪The study showed a significant difference in the cytological finding between newly‬‬ ‫.)000 = ‪discovered patients and patients under treatment (P. value‬‬