Frequency of Human Immunodeficiency Virus, HBsAg , HCV and Syphilis Infections In Blood Donors In Khartoum state

Abstract

Blood transfusion is essential and vital in the successful treatment of many malignant and nonmalignant hematological disorders. Blood transfusion is an important mode of transmission of infections to recipients. Although risk may be reduced by the vigorous screening of donors. The aim of this study to determine the frequency of human immunodeficiency virus, hepatitis B and C viruses and syphilis infections among blood donors in National Directorate of blood transfusion service at Khartoum state. This is aretrospective cross sectional study was conducted in the period between March 2014 to May 2014. Donors were selected by the standard criteria for donor fitness and screened for HIV, HBs, HCV and syphilis by ELISA. A total of 5100 donors were tested and analyzed by SPSS version 16 . Out of 4014 (78.7%) were family donors and 1085 (21.3%) were voluntary donors. The frequency of HIV was 0.3% in the donors, and in HBV, HCV and syphilis was 5.9%, 0.5% and 3.8% respectively in total donors. Conclusion: The positivity of hepatitis and syphilis was more in family donors as compared to voluntary donors. No voluntary donor was found to be positive for HIV. The present study concluded that motivating voluntary blood donors is the most effective way of ensuring adequate supplies of safe blood on a continuing basis