Cytomorphological Pattern of Renal Failure Patients Urine on Dialysis

Abstract

This study was conducted at Ahmed Gasim hospital, cardiac and renal transplation center during the period from August 2008 to April 2009.it was aimed to assess the cytomorphological changes . In this study the cytodiagnostic urinalysis was tested to determine its diagnostis value among dialysis patients ( case ) and renal failure patients not on dialysis (control). One hundred and fifty patients with renal failure and on dialysis were included and evaluated clinically , twenty five renal failure patients not on dialysis were taken as control. Urine specimens were macroscopically examined and subjected to a multiparameter reagent-strip analysis. Papanicolaou stain and MGG stain were done on cytocentrifuge preparations and the blood cells, renal cells,candida and casts examined in a standardized fashion. The study found that the case group of patients on dialysis have reduced the chance of inflammatory changes 44(29.3%) compared by controls whom were not on dialysis 13(52%), the inflammatory changes were less common after dialysis. Examination of cytological smears revealed no cytological atypia , Furthermore, different infectious conditions were detected like candida, Which was in cases 13(8.7%)and in controls 1(4%). RBCs and Casts were less frequent in cases compared to controls, in cases RBCs 127(84.7%), Casts 121(80.7%).In controls RBCs 25(100%), Casts 24(96%). That means that haemodialysis improves urinary cytomorphlogical picture.