Evaluation of Doppler indices and Measurement For Umbilical Artery In Patients with pre-Eclampsia

Abstract

Preeclampsia is one of the leading causes of maternal mortality and is responsible for considerable perinatal morbidity and mortality. This study aims to evaluate Doppler indices and measure umbilical diameter in patients with pre-eclampsia. This was a prospective, cross-sectional, hospital-based, case-control study of 30 normotensive (controls) and 30 pre-eclamptic (cases) women at Khartoum Teaching Hospital; between the period of December 2014 – June 2015. All patients were scanned for obstetric ultra sound and Doppler indices (RI, PI) were evaluate for both control and pre-eclampsia patients. The mean umbilical cord diameter for control subjects was (14.47 mm +/- 1.87 SD), for subjects with mild pre-eclampsia it was (13.65 mm +/- 1.2 SD). The mean pulsatility index for normotensive participants (controls) was (0.99 +/- 0.17 SD), that of participants with mild pre-eclampsia was (1.68 +/- 0.33 SD) and that of subjects with severe pre-eclampsia was (2.11 +/- 0.06 SD). The mean R.I of normotensive participants (controls) was (0.59 +/- 0.05 SD), it was (0.94 +/- 0.05 SD and 1.14 +/- 0.068 SD) for participants with mild and severe pre-eclampsia, respectively. The umbilical cord diameter was found to be larger in the normal than the pre-eclampsia patients as well as the Doppler indices were found to be significantly increase in pre-eclampsia patients.