Seropravelance of Rotavirus among diarrheal children at Algadaref Pediatric Hospital in Agadaref State, Sudan

Abstract

This study was conducted for serological detection of rotavirus antigens in stool of vaccinated children with diarrhea in Algdaref State during the period from September to December 2015. Stool specimens were collected from 92 children less than three years of age suffering from diarrhea in Algadaref Pediatric hospital. All the samples were tested for the presence of rotavirus antigen using rapid immunoassay and ELISA technique. The results obtained were processed and statistically analyzed using person chi-square test. The rotavirus antigens were detected in 19 samples (20.7%) out the 92samples examined by rapid immunoassay and 58 samples (63%) out the 92samples examined by ELISA. Most of positive cases were in children less than one year of age (60.3%). The study showed that, there was no significant difference (p=value 0.186) between males children (62.1%) and females (37.9%) contracting the disease. Most of rotavirus infection was reported among children who were suffering from vomition (81%) and fever (67.2%). The study showed that infection by rotavirus was not affected by age (p=value 0.419), type of feeding (p=value 0.063) and clinical presentation (vomiting and fever).