Sero-prevalence of Brucellosis among women with history of abortion in Khartoum State

Abstract

This was a descriptive, cross-sectional study conducted to determine prevalence of human brucellosis and assess the detection of Brucella antibodies by using Rose Bengal Plate Test (RBPT), modified Rose Bengal Plate Test (mRBPT), and Slide Agglutination Test(SAT), among women with history of abortion in Khartoum State from May to July (2015) on a total of one hundred and twenty (n=120) samples. All subject examined in this study were from different age groups and different times of abortion, 8/120(6.7%) of the screening women were positive for Brucella abortus antibodies by mRBPT, 5/120(4.2%) by RBPT and SAT. As for B.meletensis, only 2/120(1.7%) were positive by SAT. The highest prevalence was found on women age between 20-37 years, while the low rate was found in pregnant women aging between 38-46 years. According to frequency of abortion, 37/120(30.9%) of tested women aborted once, 64/120(53.3%) twice, and 19/120(15.8%) had abortion more than two times. When examined by mRBPT, positive cases were 3/37(8.1%) among those who had abortion once, 3/64(4.7%) among twice abortion and 2/19(10.5%) among women who had more than two time abortion.. The Results in this study showed that the mRBPT was more sensitive than RBPT and SA