Detection of Anti cytomegalovirus IgG and IgM among Women with History of Abortion in Khartoum State Hospitals

Abstract

This was a cross sectional study aimed to determine the frequency of CMV antibodies (IgG, IgM) using ELISA technique among women with history of abortion from Khartoum State hospitals from June to October (2015). Eighty nine blood samples were collected from aborted women.The women included in this study varied in number of abortion from once (20), to two or more (69) as well as age with mean age of (31.79) years.The samples were tested by ELISAand it was found that 87 (97.8 %) were positive for CMV IgG, while all the samples were negative for CMV IgM. In this study there was insignificant relationship between CMV IgG and number of abortions, and insignificant association between age groups and the IgG results but there was significant relationship between ag groups and number of abortions (P. value 0.001) The study concluded that screening women with history of abortion for the presence of anti CMV IgG using ELISA alone is of a limited value; hence, it is necessary to evaluate CMV infection using advanced techniques such as polymerase chain reaction (PCR).