Incidence of Enteroviruses Infections In Cases of Aseptic Meningitis With Emphasis on Enterovirus 71 In Khartoum State

Abstract

This study was carried out to determine the incidence of Enteroviruses among aseptic meningitis with emphasis on Enterovirus 71 (EV71) in Khartoum, Sudan. Cerebrospinal fluid specimens were collected from 89aseptic meningitis patients from different Khartoum Hospitals (Mohammed Alamin Hamid Hospital, Soba Teaching Hospital, Omdurman Military Hospital, Alban Gadeed Teaching Hospital and Police Hospital) within February to May 2015. Among 89 aseptic meningitis patients, 43 (48%) were male and 46 (52%) were female. The patients age between 1 day to 30 years. The collected specimens were assayed to detect Enteroviruses and EV71 RNA using reverse transcriptase polymerase chain reaction (RT-PCR) technique. 46 (52%) specimens were found positive for Enteroviruses. Out of 46 specimens, 10 (22%) specimens were found positive for EV71. In conclusion, the incidence and the existence of Enteroviruses with emphasis on EV71 was conducted. Further study using various diagnostic methods should be considered to determine these viruses on national level.