Assessment of Serum Levels of Chromium and Magnesium among Sudanese with Bronchial Asthma

Abstract

This is a case control , hospital based study was carried out to measure the levels of chromium and magnesium in Sudanese asthmatic patients attending alshaab teaching hospital, Khartoum state, during the period from May to June 2015 Fifty Sudanese asthmatic patients, including 30 males (aged 20-90years), and 20females (aged 18-80years), were enrolled in this study, also fifty apparently healthy individual to serve as control group (aged 18-90), including 30 males and 20 females. Five ml of venous blood were collected from each participant, the serum obtained; chromium and magnesium levels were measured by Atomic absorption spectrophotometer (AAS) and Mindary BS 200respectively. Statistical analysis of obtained results revealed that; mean of serum levels of chromium was significantly lower among asthmatic patients compared to control group (p value 0.000), and no significantdifference in serum levels ofmagnesium between asthmatics and controlgroup (p value 0.314).Also results showed that asthmatic patients serum levels of chromium and magnesium are not effected by age (p value Cr0.644, Mg 0.808) and sex (p value Cr0.135, Mg 0.102) and body mass index (p value Cr0.968, Mg 0.524) and duration of disease (p value Cr0.184, Mg 0.550) . In conclusion, this study suggests that low Cr level may have a role in bronchial asthma in Sudan; but Mg level not effect ,also age , BMI , and duration of disease there is no effect on theserum trace elements levels.