Study of Platelets Count and Indices in Malaria patients in Northern State

Abstract

This is a case control study conducted at Dongola Hospital ,in the period from January to April 2015. The study aimed to study platelet count and indices in sudanese malaria patients . One hundred blood samples were collected in ethylene Diaminetetraacitic acid (EDTA)containers ,70 samples from malaria patients and 30 samples from healthy volunteers as control , platelet counts and platelet indices were determind using automated hematological analyzer (Sysmex BC-3000 plus). The result showed that 43 patients (61.4%) with thrompocytopenia , mean±SD of platelet counts in patients decreased significantly compared to controls (135±16.1×109 vs 280±63.9×109cell/L respectively ,P.value 0.000), MPV in patients was decreased in patients compared to control group (7.68±051 vs 8.56.62 fl respectively ,P.value 0.000) ,PCT was decreased in patients compared to control group (0.191±0.06% vs 0.2350.065% respectively,P.value 0.002) ,PDW was showed no significant defferance in patients compared to control group (15.69±1.05 vs 15.5786 fl ,P.value 0.595). The study concluded that malaria altered the blood platelets count cousing thrompocytopenia and decrease mean platelet volume,plateletcrit but no significant deferance in platelet distrebutioon width .