Total count and absolute values of White Blood Cell in patients with Diabetes Mellitus Type2

Abstract

This case control study, conducted in Khartoum during the a period from March to august 2015.in jabber AbuEeaz specialize center .The aim of this study was study total countandabsolute values of white blood cellinSudanese patients with type2 D.M. Eightysample were collected from type2 diabetic patients and twenty control sample were collected from healthy non- diabetic volunteer, aquestionnaire was designed to collect information about the study group such as sex, ageand duration of disease. 2.5 ml of venous blood was collected in EDTA anticoagulant container. Automated hematological analyzer (sysmex KXN_21)was used to measure total, absolute values of white blood cell, the result were analyzed by SPSS computer program. The majority of the case were male,frequency (45),percentage ( 56.2% ) while the female frequency(35,)percentage ( 43.8% ), the control, the male frequency (11),percentage ( 55% ) while the female frequency(9)percentage ( 45% ).The mean of age of study subject is51.86 ± SD 10..97 the minimum age is 28years and the maximum age is 77years.The result indicates that for patient there was slightly high significant increase in mean of total and absolute values of white blood cell, the mean±SD in case group 9.72 ±3.48 in control group 4.51± 0.79 for total counts, 6.68 ± 3.57 and 2.26± 0,49 for neutrophil, 2.22±0.87 and 1.80±0.39 for lymphocyte, 0.81 ± 0.41 and 0.46 ± 0.19 for mixed cell..(p.value≤ 0.05) . This study show that there was no statistically significant variation in total counts and absolute valuesof white blood cell according to the gender the mean-SD in male group 9.00 -3.89 in female group 8.26 – 3.60 for total counts, 6.17± 3.76 and 5.32± 3.51 for neutrophil, 2.04 ± -0.76 and 2.25 ± 0.86 for lymphocyte, 0.79 ± 0.45 and 0.69 ± 0.32 for mixed cell.( p.value≥0.05.. Also our study indicate there was no statistically significant correlation between total ,counts and absolute values of white blood cell and age of study population.(p.value≥ 0.05) .when the total counts and absolute values of white blood cell analysis within duration of diabetes mellitus ,the result showed statistically significant correlation .(p.value≤ 0.05) . Itconcludes thatthe total counts and absolute values of white blood cell were increase as the result of type2 diabetes mellitus.