Stability Evaluation of Ciprofloxacin Drug

Abstract

This study carried out the assay of the active material in ciprofloxacin drug with Shanghai and Blue Nile companies were found to be 96.8% and 100.56%, respectively. In this work the dissolution testing achieved for six samples of ciprofloxacin drug (1) (2) (3) (4) (5) (6) for two different companies (Shanghai and Blue Nile), the percentage of dissolved of ciprofloxacin in water are (96.6, 96, 100.3, 95.7, 96.9, 95.9) % respectively for Shanghai company and (97.2, 97.3, 99.8, 95.7, 97.5, 96.5) % respectively for Blue Nile company. And some physical properties tests were achieved. The hardness, thickness, disintegration, weight variation, and friability, for Shanghai company 19.7kgf, 6.18 mm, 2:56 minute, (721.74g – 720.25g), and 0.1% respectively, and for Blue Nile company are 17.2kgf, , 4.7 mm, and 2:23 minute, (721.74g – 720.25g), and 0.98% respectively.