Evaluation of Haematological Changes in Chronic Renal Failure Patients Undergoing Haemodalysis and the Relationship with their ABO Blood Group

Abstract

This study was conducted at the Military Hospital at Aref Center of Dialysis during the period from March to June 2015, to evaluate the haematological changes in chronic renal failure patients under haemodialysis and to study the relationship of ABO blood group with chronic renal failure. Hundred renal failure patients were enrolled in this study and thirty healthy individuals as a control group. Basic information of the participants were collected through a questionnaire. Two and half ml of blood were collected from each participant. Automated haematological analyzer (sysmex KX-21N) was used to measure complete blood count. The blood samples were tested for ABO blood group by the tubes method. The major of the participant were male(36%),the aged range was (40-59 year),they were on hemodialysis for more than three year (49%),twice in a week (93%).All the participants were recived medication. Chronic renal failure patients showed lower significant values than the control group for: Hb (10.2+2.1 vs 12.7+1.7) g/dl, RBCs count (3.5+0.8 vs 4.5+0.6) 106 /µl, PCV (33.5+8.8 vs 39.6+5.5 %) and platelets count (197.3+88.1 vs 270.2+63.6) 103 /µl. Chronic renal failure patients showed significant value than the control group in MCV (93.1+6.0 vs 90.0+5.4 fl). The mean leucocyte count (5.1+1.7 vs 5.4 +1.6) 103/ µl, MCH (28.9+2.2 vs 28.1+1.9) pg and MCHC (31.1+1.2 vs 31.2+1.2) g/dl, showed no statistically significant changes. No association was found between chronic renal failure and ABO blood group. The distribution of ABO blood group among chronic renal failure patients was O (37%) > A (31%) > B(28%) > AB(4).