Effect of Hemodialysis on the Albumin, Calcium and Phosphorus in Patients with Renal Failure

Abstract

This study was carried out to measure serum levels of the calcium, albumin and phosphorus in patients of renal failure under hemodialysis. Eighty samples were collected from patients in period between January to March 2015, chosen randomly from ALnaw teaching hospital , and forty apparently, healthy individuals as controls, to assess the effect of hemodialysis on calcium ,albumin and phosphorus level. Measure serum calcium, albumin and phosphorus by using biosystem, and results were analyzed using statistical of package social science (SPSS), computer program. The study showed that the serum levels of calcium, albumin were significantly decreased, (p-value =0.05), (p-value =0.03) in the Sudanese patients under hemodialysis group. And the serum levels of phosphorus were significantly increased, (p-value =0.00 in the patients under hemodialysis group Mean ± SD for controls versus cases (7.8±.1.1 versus 10.5±12.3) for calcium (2.7±0.8 versus 4.5±5.7) for albumin (5.0±1.2 versus 3.6 ±1.1) for phosphorus Also In this study showed that there was no significant difference between the levels of calcium, albumin and phosphorus according to gender "male or femle". The results as follow:

Mean ± SD for male versus gender (7.7 ±.1.2 versus 8.0±0.9) mg/dl, p-value≤0.2) for calcium (2.7 ±0.7 versus 2.6 ± .9) mg/dl, p-value≤0.83) for albumin. (5.1±1.2 versus 4.8± 1.2) mg/dl, p-value≤0.35) for phosphorus According to causes of chronic kidney disease the results of this study showed that; hypertension, diabetes and family history are the most common causes in Sudan. It is concluded that; the levels of calcium, albumin were significantly decreased, in the patients with renal failure under hemodialysis, And the serum levels of phosphorus were significantly increased, in the patients with renal failure under hemodialysis.