Effect of Cigarette Smoking and Passive Smoking in Cellular Constituents of the Blood in Male Sudanese Smokers

Abstract

This is an analytical observational descriptive study, conducted to determine the effect of cigarettes smoking and passive smoking of male Sudanese smokers in the period from January 2011 To June 2011. Seventy (70) active smokers and thirty five (35) passive smokers were informed about the study and informed consent for participation was obtained . 2.5 mls of venous blood was collected in ethylene diamine tetra acetic acid (EDTA)containers and investigated for complete blood cell count (CBC)[using semi automated hematological analyzer(sysmex KX 21N)]. And statistical package for social science (SPSS) computer program version 16 was used for data processing. The results showed that there was no significant difference between active smoking and passive smoking on CBC ( p value<0.05). Total erythrocytes, hemoglobin concentration and packed cell volume was significantly increased in smokers and passive smokers when compared with non smokers (p value= 0.000, 0.009, 0.000) respectively. Total leukocytes count was significantly increased in smokers and passive smokers when compared with non smokers (p = 0.000). There is no significant differences in smokers, passive smokers and non smokers in neutrophil%, lymphocyte%, MXD%, and platelet count (p = 0.084, p = 0.249, p = 0.821 and p=0.37) respectively