Electrolyte disturbance in Sudanese patients with cancer

Abstract

This study was performed in Khartoum state during the period from January to April 2015. The aim of the study was to assess the effect of cancer on sodium, potassium, Calcium and phosphorous levels as a markers of electrolyte imbalance in Sudanese cancer patients.90 blood samples were collected divided to 50 blood sample from Sudanese cancer patients, and 40 samples from apparently healthy individuals as control group for the comparison . plasma levels of sodium and potassiumwere estimated by iron selective electrod while levels of calcium and phosphorous were estimated by spectrophotometer (Biosystem310). Statistical analysis showed that there is a significant decrease in the sodium level in patients when compared with control group (mean±SD) (132.65±6.6)and(138.75± 2.4) respectively withP value=0.000. and significant decrease in the potassium level in the breast cancer patients when compared with the control group (mean±SD) (3.3±1) (4.±0.53) respectively withP value=0.039. While showed no statistical significances in potassium, Calcium , phosphorous level in, myeloid, lymphoid and cervix cancer when compared with control groups were(3.58±.85),(4.2±.67),(3.8±.65)(4.±0.53) P values0.290 ,0626 ,671 respectively.(8.46 ±1.2) ,(8.63 ±1.17),(8.25 ±.96),(8.45 ±.38)(8.83± .52), Pvalue0.699,0.314,0.144respectively.(3.25±1.1),(3.3±.78),(3.7±.31),(3.5±.33),(4.34±0.48) P values0.313 , 0.961 , 0.462 respectively. In this study it was concluded that plasma sodium level decreased in some types of cancer and potassium level is decreased in breast cancer. While level of calcium and phosphorous were not affected in myeloid , lymphoid ,cervical cancer patients.