Assessment of Serum Albumin: Globulin ratio among Enteric fever Patients in Northern Sudan

Abstract

This is descriptive analytical case control study was conducted in Merowe locality, Northern state, Sudan, during the period April to June 2014, the study aims to assess the effects of enteric fever on serum total protein, albumin, globulin and albumin: globulin ratio in typhoid males and females patients and to compare their results with healthy, and comparison between healthy and infected males and females using colorimetric method. The results reveal that, serum total protein and globulin were significantly increased in typhoid patients compared to healthy P. value =0.000. on the other hand, serum albumin and albumin: globulin ratio was significantly decreased in typhoid patients compared to healthy P. value =0.000 . No significant differences in serum total protein, serum albumin and serum globulin between males and females patients regarding the effects of the typhoid. Correlations between the titers and serum total protein, albumin and globulin were negative. The study concluded that, Enteric fever increases total serum protein and serum globulin and decreases serum albumin and albumin: globulin ratio irrespective of genders.