Design and implementation of NON-INVASIVE MALARIA DETECTION system

Abstract

This research focuses on quantify presence of malaria pigment (hemozoin) in blood stream by measuring the two properties of light interaction with hemozoin crystal: scatter angle and absorption of laser infrared when interacting with hemozoin particles on application of a magnetic field and pressure force in a non-invasive way. The prototype contains Laser infrared source, permanent magnet and embedded system (SOC) in-order to diagnose malaria type and prove the relationship between infrared scatter angle, absorption, and hemozoin presence. And combine between two results to find the best non invasive way which present better result than other method used. Fifty two total cases taken from Sudanese Germany centre laboratory divided into two parts: thirty two positive and twenty negative readings had been tested with the prototype which gives test accuracy of (90.38 %)and sensitivity percentage (93.7 %), with combining results of scatter angle 5ᵒ and absorption value between (290 mV to 449 mV) for malarial cases, (2ᵒ to 4ᵒ) and (450mV to 1248mV) for non-malarial cases . Non-invasive, less pain and more comfortable malaria test was presented at small area with high performance and small duration (50 sec\person), by this study.