Seroprevalence of Cytomegalovirus Infection among Neonates with Congenital Anomalies

Abstract

This is a qualitative, descriptive, cross-sectional, hospital-based study , It was conducted among neonates with congenital anomalies attending Omdurman Maternity Hospital, Alshaab Teaching Hospital, Ibrahim Malek Teaching Hospital in Khartoum State, During the period from September to December 2013. A total of 92 neonates with congenital anomalies (n=92) were included in this study,39 (42.4%) of them were males, and 53 (57.6%)were females. There age ranged from 1 day to 4 months (mean2.6 month). Serum samples were tested for Cytomegalovirus IgM by a capture enzyme- linked immunosorbent assay (ELISA). Data were analyzed by SPSS version 16.0 computer software. The results obtained showed that while 2 (2.2%) out of 92 neonates with congenital anomalies were Cytomegalovirus IgM positive, 90(97.8%) were Cytomegalovirus IgM negative. One (1.1%) of 92 neonates with congenital anomalies has neural tube defect (NTD) and the other one (1.1.%) has hydrocephaly( HC). From the above findings it is concluded that, there was 2.2 % of neonates with congenital anomalies are Cytomegalovirus IgM positive in Khartoum state. There is no differences in the proportion between congenital anomalies associated with Cytomegalovirus.