Measurement of Reticulocyte Counts and the Effects of Abortion on Erythropoiesis in Sudanese Pregnant Women

Abstract

This is a descriptive analytic study which was done during the period from March to June 2014 at Kosti Teaching Hospital - White Nile State. It aimed to estimate Red blood cell count, Haematocrit, Reticulocyte count, and to calculate corrected reticulocytes count (CRC), absolute reticulocytes count (ARC) and rericulocytes production inex (RPI) among sudanese pregnant women. 130 Blood samples were collected; 75 samples of which from pregnant women with no previous abortion, 25 samples of which from pregnant women with history of abortion and 30 samples from non pregnant as control group. Blood was drawn in EDTA anticoagulant treated containers. The count of Red Blood Cell and Haematocrit were performed by using hematological analyser. The reticulocyte count was manually determined using microscope. Data were analyzed by using Statistical Package of Social Science “SPSS” computer program and compared with control group. The result showed that: PCV of pregnant women was 0.35 L/L, compared to 0.27 L/L of control AND 0.34L/L of previous abortion. RBC’s count of pregnant women was 4.3*106 c/µl, compared to 3.1*106 c/µl of control and 4.0*106 c/µl of previous abortion. Reticulocyte of pregnant women was 1.3%, compared to 0.5% of control, and 2.1% of previous abortion. CRC of pregnant women was 1.0%, compared to 0.2% of control and 1.7% of previous abortion. RPI of pregnant women was 0.8, compared to 0.3 of control and 1.2 of previous abortion. Conclusion: the results suggested that Reticulocyte count and RPI are elevated by pregnancy and abortion.