Measurement of Complete Blood Count (CBC) in alcohol consumer – Khartoum 2014

Abstract

This is a prospective case control study to investigate the effect of alcohol consumption on complete blood count (CBC) of alcohol consumers in Khartoum State from April to July 2014.The participants were 80 apparently healthy adult males; 50 of them are alcohol consumers and 30 are non-alcoholic (control).Their age was (41 ±7.3years).A questionnaire was constructed to obtain information about the participants after an informed verbal consent from all the participants. Ethical approval was obtained from the College of Medical Laboratory Sciences-SUST. The educational level of the subjects was 74% primary, 16% secondary and 10% had higher education. 84% of the alcoholic's participants use local drinks while the rest16% drink imported alcohol. The duration of alcohol consumption was 5-20years. Blood was collected from all participants into EDTA containers then CBC was carried out immediately after collection; using an automated hematological analyzer (Sysmex KX-21N). Data obtained was analyzed using software program statistical package of social science (SPSS.V.11.5).The results obtained from alcoholic compared with the control were insignificantly different (P≤0.05) with regard to erythrocytes count (4.53±0.6),hemoglobin level (14.28±0.23) hematocrit(39.26±0.57), mean cell volume(86.75±1.54), mean cell hemoglobin (29.46±0.33),total leucocytes count (6.33±1.7), monocytes% (4.3±0.3), eosinophil%(1.88±0.1), basophil %(0.48±0.08) and platelet count(251.4±5.3). The alcohol consumers registered significantly higher values (P<0.05) than the control for RDWCV(13.65±0.17), absolute lymphocytes count (2.9±0.8), and significantly (P≤0.05)lower values than the control for absolute neutrophil count (2.96±1.45) and platelet count(P.V 0.06). Macrocytes, target cells, crenated cells, few fragmented cells were found in the peripheral blood of some alcoholic subjects.