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Serodetection of Hepatitis B Virus among Nurses at El-obied city Hospital North Kordofan State

Thu, 29 Dec 2022 00:00:00 GMT

Title: Serodetection of Hepatitis B Virus among Nurses at El-obied city Hospital North Kordofan State Authors: Ahmed, Wadah Adam Omer; Supervisor, -YousifFadlallaHamedelnil Abstract: Hepatitis B infection is one of the world's major infectious diseases and nurses have a high risk of occupational exposure to Hepatitis B Virus. This descriptive cross sectional study aimed to determine sero-prevalence of Hepatitis B virus and to determine the possible association between Hepatitis B virus and some risk factor among Nurses workersat El-obied city Hospitals North Korfofan Stateduring a period from May to October 2022. Structured questionnaire was used to collect both demographic and clinical data,Venus blood (3 ml) was taken from each participantby standard procedure,were put in plain containers to clot then centrifuged at 5000 rpm for5 minutes and serum was obtained and kept at -20ͦ C until used . The serum sample were examined by Enzyme Linked ImmunosorbentAssay (ELISA) to detect HBsAg. A total of (n=78) nurses in EL-obeid city were included in this study, in which 7 (9%) were males and 71 (91%) were females, mostly were at age between 20-30 years (63%). Among Nurses there were 4 (5.1%) positive for HBs Ag and other were negative(95%). Among these There were3/4 (75%) females were positive. for HBs Ag and 1/4 (25%) males waspositive. According to age groups, there was 2(50%) of the positive result between 20-30 years ,1 (25%) in age range from 30 to 39 years and 1(25%) in age more than50 years were positive for HBs Ag. There was 2 (2/4 (50%))of positive HBsAg nurses had accidental needle stick and the othersdidn't expose to any of the possible risk factors were HBs Ag positive . The study indicated insignificant association between Hepatitis B infection and effective factor ( P> 0.05),gender ,age , accidental injury ,blood transfusion , surgicaloperation ,renal dialysis , (P.value: 0.25 , 0.75 , 0.71,0.50 , 0.98 , 0.74 , ,respectively ). This study concluded the frequencyof hepatitis B virus among the nurses are normal. Description: Thesis

Frequency of Helicobacter pylori IgG Antibodies among Diabetic patients in Khartoum state, Sudan

Mon, 12 Dec 2022 00:00:00 GMT

Title: Frequency of Helicobacter pylori IgG Antibodies among Diabetic patients in Khartoum state, Sudan Authors: Suliman, Moaz Ismail Hashim; Supervisor, -Yousif Fadlalla Hamed Elnil Abstract: This study was conducted for serological detection of Helicobacter pylori antibodies in serum of diabetic patients and non diabetic individuals in Khartoum State during the period April to September 2022. Blood samples were collected from 180 individuals ( 120 diabetic patients and 60 non diabetic patients ),Two milliliters of blood sample was collected in plain containers from each diabetic patient and non diabetic patient and let it until clot and serum was separated used centrifuge and tested for the presence of Helicobacter pylori IgG antibodies using rapid test device(ECO test). Helicobacter pylori IgG antibodies were detected in 35 (58.3%) of the diabetic patients that treated with insulin total of 60 patients, and detected in 39 (65%) of the diabetic patients treated with anti diabetic agent total of 60 patients , in the non diabetic individual were detected in 27 (45%) positive total of 60 non diabetic individuals, It was in agreement with other studies,in (Vafaeimanesh et al.,2015) found that the prevalence of HP seropositive was (65.9%) versus (50.5%) in diabetic and non diabetics, respectively, and the difference was statistically significant, this result is close to present study, (Jamshid et al.,2014) found that the prevalence of Helicobacter pylori infection was (55.8%) in diabetics and (44.2%) in non diabetics ,(Roussos and Angeliki ,2002) reported that the prevalence of H. pylori between diabetics (37.3%) and non diabetics (35.2%) .The high frequency of positive subject among diabetic treated with anti diabetic agent 39 (65%) and the correlation was statistically not significant more than (P<0.05).And detection of Helicobacter pylori should be routine in diabetic patient and further studies in diabetic mainly those treated with antidiabetic agent. Description: Thesis

Assessment of Plasma Total Cholesterol, Low Density Lipoprotein Cholesterol and Uric Acid among Sudanese patients with Type 2 Diabetes Mellitus in Khartoum state

Wed, 21 Dec 2022 00:00:00 GMT

Title: Assessment of Plasma Total Cholesterol, Low Density Lipoprotein Cholesterol and Uric Acid among Sudanese patients with Type 2 Diabetes Mellitus in Khartoum state Authors: Ebrahim, Basma khider; Supervisor, -Gahda Abdelrahman Elfadil Abstract: Background and aim of study: Lipid abnormalities in patients with type 2 diabetes are a major problem and associated with the increased risk of cardiovascular disease (CVD). The study aims to estimate total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), uric acid (UA) and HbA1c among type 2 DM. Materials and Methods: This was cross sectional hospital-based study conducted from March to July 2022, at different diabetic centers(Sad Roshwan and Gabber Abo aleis )in Khartoum state among 300 Sudanese patients with type 2 Diabetes mellitus. 5 ml of blood samples were collected from type 2 Diabetes mellitus patients, 2ml put in EDTA container to estimate HbA1c level, and 3ml in heparin in order to estimate TC, LDL-C, UA level which measured by using enzymatic method and spectrophotometer device, and commercial reagent kits from Bio system company. The data obtained were analyzed by using SPSS version 26 computer program. Results: study showed 73% (n=219/300) of study group were poor glycaemic patients (HbA1c >7%). TC and LDL-C were significantly increased in poor glycemic type 2 DM, TC (245.1 ± 48.7 mg/dl vs 189.1± 23.9 mg/dl); LDL-C (158.4± 38mg/dl vs (110.5±21.5 mg/dl) when compared with good glycaemic. Moreover; HbA1c was significantly positive associated with TC (r=0.576; P=, 0.000). and LDL-C (r =0.552, P=0.000). Study revealed that there was insignificant difference in mean of UA in good glycemic control when compared with poor glycemic control. Conclusion: Sudanese with type 2 diabetic patients poor glycaemic control have increased plasma TC and LDL-C, HbA1c was significantly positive associated with TC and LDL-C. Study revealed that there was insignificant difference in mean of UA in good glycemic control when compared with poor glycemic control. Description: Thesis

Frequency of Vaginal Thrush among Symptomatic Pregnant Women in Khartoum State, Sudan

Sat, 21 Jan 2023 00:00:00 GMT

Title: Frequency of Vaginal Thrush among Symptomatic Pregnant Women in Khartoum State, Sudan Authors: Hassan, Enaam Mokhlis Fth Alrhman; Supervisor, -Hind Haidar Ahmed Abstract: Reproductive tract infection is an important public health problem worldwide especially in developing countries. Vaginal candidiasis is a fungal or yeast infection of the vulva and/or vagina, that caused by opportunist yeast, this infection is not a sexually transmitted one. Women have a very high chance of developing vaginal candidiasis and probably have at least one during their lifetime. Having a pregnancy or diabetes makes them more vulnerable to this vaginal infection. The current study conducted to determine the frequency of vaginal candidiasis and the occurrence of Candida species in pregnant women in Khartoum State. In this cross sectional descriptive study, two high vaginal swabs (n=200) were collected from 100 pregnant women, present with vaginal discharge, and other symptoms of vaginal candidiasis attended Omdurman Maternity Hospital and Alribat Teaching Hospital from the period between July to October 2022, Candida species were isolated and identified by conventional method, Germ Tube Test (GTT) and Chromagar method. Data was analysed with statistical package of social science (SPSS). In this study 28 / 100 (28%) swab samples showed a growth on the Sabouraud's dextrose agar and 72 / 100 (72%) were negative yeast growth. GTT and Chromagar method were used to differentiate between candida spp. According to GTT there were 15 out of positive 28 isolate (53.5%) Candida albicans and 13 (46.4%) Non albicans Candida (NAC). 18 (64.2%) were Candida albicans, 6 (21.4%) Candida tropicalis, 3 (10.7%) Candida krusei and 1 (3.5%) other species according to Chromagar method. Insignificant statistical association was found between vaginal candidiasis with age, duration of trimester, DM and past vaginitis, while significant statistical association was found between vaginal candidiasis with occupation, education level, antibiotic treatment and clinical symptoms. In conclusion this study showed that vaginal candidiasis infection was common in pregnant women and frequency was significantly higher in the third trimester. Candida albicans was the predominant species, and there was an association between vaginal candidiasis with occupation, education level, antibiotic treatment and clinical presentation. Description: Thesis