Abstract:
Tuberculosis is an infectious disease caused by various strains of mycobacterium, usually
mycobacterium tuberculosis. The aim of this study was to measure platelets, C-reactive protein
and fibrinogen levels,
This was analytical case control study, conducted during the period from June to August 2013,
40 Sudanese with tuberculosis were selected as test group from Abo Anga Hospital in Khartoum
state. The results of test group was compared with control group which included 20 apparently
health volunteers. Blood specimens were collected from both groups and platelets, C-reactive
protein and fibrinogen levels were measured. Gender of the test group were matched with the
control group, Platelets was measured using automated hematology analyzer sysmex KX-21 N,
commercial kits from NycoCard® and NycoCard® CRP Single Test were used for measuring C-
reactive protein, commercial kits from FIBRI PREST ® 2 were used for measuring fibrinogen
levels, the results were analyzed using SPSS computer software program (version 14.0).
The result of this study indicated that there was a significant increase in the mean levels of
platelets (393.45 ± 158.2
x103/ul) and C-reactive protein (6.5 ± 2.24 mg/l) and fibrinogen
(389.58 ± 113.7 mg/dl) of patients compared with control group (p value 0.00).
In conclusion tuberculosis patients in this study have thrombocytosis, increased C-reactive
protein and elevated fibrinogen level.
