Abstract:
A cross sectional study was undertaken at Khartoum state between November 2008-
Fabruary 2009. A total number of 50 relatives of beta thlassemia were consecutively
recruited . Hb F level was measured by an akali denaturation procedure. This study
aimed at assessing fetal haemoglobin in the parents and siblings of beta thalassemia
patients. The study reveled that , the age groups were found to rang from 3 to 70 year.
98% of the study population was found to have elevated Hb F level. There was no
significant association between the age groups of subjects and the level of fetal
hemoglobin among relatives of beta thalassemia patients. No statistical significance was
observed in sex and fetal haemoglobin level among realtives of beta thalassemia
patients. Call for psychosocial study should be conducted in order to discourage
marriage among relatives , to mitigate and inhibit the expression of beta thalasemia gene
specially among those at high risk group of beta thalassemia.
