Abstract:
This study is a descriptive cross sectional analytical study, aimed to
determine the frequency of sickle cell anaemia and sickle cell trait in
patients referred to madani peadiatric hospital at EL-Gazeera State,
during November to February. 27 families with 96 individuals, with
different ethnic origins, involving 33 (34.3%) are patients with sickle
cell anaemia, age ranged between 5month to 16years, 57 (59.4%) are
sickle cell trait age ranged between 2.5-55years in which (33.3%) are
males, and (66.7%) are females, and 6 (6.3%) are normal individuals. All
of these families their tribes from western Sudan, Hawsa tribes, branch
of Afro-Asiatic family, represent high percentage of sickle cell anaemia
(45.4%) and (43.8%) sickle cell trait, followed by Brgu tribes, the Nilo-
saharan group with (15.1%) of sickle cell anaemia, and (12.3%) of sickle
cell trait, Brnu tribe showed high percentage of sickle cell trait (22.8%),
after Hawsa tribes. Most of the patients in this study had parents from
the same ethnic group (92.6%), indicating the high degree of within-
group marriages, and thus the higher risk of augmenting the sickle-gene.
Mean of Haemoglobin level in patients with sickle cell anaemia is low
(6.9g/dl), while in sickle cell traits is normal (12.3g/dl). Haemoglobin F
level (%) mean in sickle cell anaemia patients increased (6.8%)
compared with sickle cell trait mean of heamoglobin F which is (2.9%).
