Abstract:
This study was carried out in Halfa algadida town which is endemic for
Schistosoma mansoni, and in Khartoum state on the bank of the White Nile
in Al kalakla al Galaa, Al kalakla al Gopa, Wad Alagale and alshigylap
regions where S. haematobium is prevalent
The purpose of this study was to detect the utility of Schistosoma bovis adult
worm antigen for diagnosis of human Schistosomiasis by enzyme linked
immunosorbent assay and to compare it with the conventional methods for
detection of Schistosomiasis.
A total number of 37 blood samples from confirmed Schistosoma mansoni
patients by stool examination, and 37 blood samples from confirmed
Schistosoma haematobium infected subjects by urine examination were
collected. Eight volunteers were included as non-endemic negative controls.
All samples were examined by ELISA technique using S.bovis antigen. The
results showed that ELISA as a diagnostic method revealed 100% specificity
in both forms of schistosomiasis, while the sensitivity was found to be 63%
for Schistosoma haematobium and 54% for Schistosoma mansoni.
In conclusion, S. bovis antigen can aid in the diagnosis of human
schistosomiasis especially if the purity of the antigen is increased to enhance
the sensitivity.
