Abstract:
This is a descriptive cross-sectional study conducted during the
period from
march to august 2013 in Radio
Isotopes Center Khartoum State (RICK), The study, aims to
evaluate serum cholicalciferol and cholesterol levels in patients
with breast cancer, in addition to correlate Cholecalciferol and
cholesterol level with risk factors of breast cancer (age, body
mass index, duration of the disease and number of Children
birth), sixty patients and thirty healthy individual as control group
were enrolled. Venus blood samples were collected and serum
obtained using standard procedure. Cholecalciferol and
cholesterol levels were carried out using ELISA and Enzymatic
method for Cholecalciferol and cholesterol respectively. The
results showed, there is significantly decreased in Cholecalciferol
level in breast cancer patients compared with control group (P –
value (0,000). mean cholesterol level showed significant
increased in patients compared with control group (P – value
(0.000). menopausal women showed low Cholecalciferol in
comparison with premenopausal women (P – value (0,041). And
there is no significant difference in the mean of serum
Cholecalciferol and cholesterol level in breast cancer classified
according to their parity (number of children), body mass index, and
duration of disease. The present study conclude that, there was
decrease in Cholecalciferol level among Sudanese women with
breast cancer especially in menopause one , The mean level of
cholesterol was found to be highest in all breast cancer patients.
The results of frequencies showed more percentage of breast
cancer among postmenopausal women.
