Abstract:
This is a descriptive prospective study to assess the cellular
proliferative activity in thyroid fine-needle aspiration (FNA) materials. The
study was conducted in Khartoum during the period from November 2008 to
March 2009. FNA Materials, were obtained from 50 patients (46 females and
4 males), with thyroid palpable lumps. Their ages ranging from 19 to 85 years
with a mean age of 40 years old.
The diagnoses of the 50 thyroid FNAs were as follows: 3 (6%) were
smears showing atypical cell, 9(18%) were showing thyroid hyperplastic cells,
34(68%) were found with normal thyroid cells and 4 (8%) were identified as
non-representative smears.
All of the nine smears that were taken from the patients with thyroid
hyperplasia and one smear from a patient with atypical thyroid cells, have
showed intense DNA staining (++) by Feulgen staining method. All smears
that were diagnosed as containing normal thyroid cells 34(68%) and 2 (4%) of
those showing atypical thyroid cells had mild staining intensity.
