Abstract:
A cross-sectional study conducted during the period November 2008 to
June 2009, compared serum levels of magnesium, urate and creatinine of 50
Sudanese patients with chronic renal failure (CRF) (as a test group), and 30
apparently healthy volunteers (as a control group). Participants in this study
were from Dr.Salma Center for Kidney Transplantation and Dialysis, Ibn Sina
Hospital and Ibrahim Malik Teaching Hospital. Age and gender of the test
group were matched with the control group. The serum levels of magnesium,
urate and creatinine were measured using, Biosystem BTS-310 analyzer,
Germany.
Serum magnesium, urate and creatinine were significantly raised in the test
group compared to the control group. Mean ± SD for the test group versus the
control group:
(2.22 ± 0.20) versus (1.90 ± 0.14) mg/dl (p = 0.03); for serum magnesium.
(6.12 ± 1.52) versus (4.17 ± 1.32) mg/dl (p = 0.01); for serum urate.
(9.45 ± 3.77) versus (0.83 ± 0.16) mg/dl (p = 0.001); for serum creatinine.
In the test group, serum magnesium, urate and creatinine showed no
correlation with the duration of the disease (r = 0.00). Serum magnesium and
urate showed a weak positive correlation with serum creatinine (r = o.35) (r =
0.33) respectively.
From this study, it is concluded that; in Sudanese patients with CRF the
serum levels of magnesium, urate and creatinine were raised. In addition,
serum magnesium, urate and creatinine are not correlated with the duration of
CRF, whereas serum magnesium and urate are weak positively correlated with
serum creatinine.
