Abstract:
Chronic renal failure is one of diseases that may
cause mortality. Patients with chronic renal failure requires
certain laboratory investigations including for example: urea,
creatinine and electrolytes.
Magnesium is one of the electrolytes that may be of
importance in the management of these conditions and may
help the nephrologists for treatment and follow up.
This case-control and cross-sectional study was carried
out at renal unit of Omdurman military hospital in Khartoum
state, to measure the plasma magnesium level in Sudanese's
patients with chronic renal failure (CRF) during the period
from November 2009 to march 2010.
Forty patients with CRF (pathological group) and 40
apparently healthy individuals as (control group) were
included in this study.
Results showed that there was a significant difference
between the means of plasma magnesium levels of the
patients group (n=40) and the control group (n=40). Mean ±
SD: (0.974±0.172) versus (0.763±0.129) mmol/l, (P= 0.00)
Results showed that there was no significant
difference between the means of plasma magnesium levels
of the males (n=27) and the females (n=13) in the patients
group. Mean ± SD: (1.0±0.14) versus (0.92±0.22) mmol/l,
(P= 0.18)
Results showed that there was no significant difference
between the means of plasma magnesium levels of the males
(n=26) and the females (n=14) in the control group. Mean ±
SD: (0.75±0.12) versus (0.79±0.14) mmol/l, (P= 0.37)
Results showed that there was a significant difference
between the means of plasma magnesium levels of the
patients males group (n=27) and the control males group
(n=26). Mean ± SD: (1.0±0.14) versus (0.75±0.12) mmol/l,
(P= 0.00)
Results showed that there was no significant difference
between the means of plasma magnesium levels of the
patients females group (n=13) and the control females group
(n=14). Mean ± SD: (0.92±0.22) versus (0.79±0.14) mmol/l,
(P= 0.07)
In conclusion this study found that Plasma
magnesium level was found to be significantly increased in
chronic renal failure and the change in plasma magnesium
level was not affected by gender.
