Determination of PT, APTT, Platelets count, Bleeding Time forAcute and Chronic Renal Failure Patients Attending Khartoum Teaching Hospital

Abstract

This study was hospital analytical case control, and it was conducted to evaluation of haemostatic mechanism among the Sudanese patient with renal diseases attending Khartoum teaching hospital throughout the period BetweenNovember2009– march2010. 60 patients were informed about the study, expected out come and agreement of participation was obtained, then the questionnaire was used to collect the information about patient's age, sex, blood groups as well as other diseases. As well 5 ml of blood were taken from the patients 2.5 ml of which were taken in tri sodium citrate anticoagulant, and the remaining 2.5 were taken in EDTA anticoagulant and were used to evaluate the haemostatic mechanism (PT, PTT, Platelets counts). As well computerized statistical package for social sciences version 11.5 was used to determine the samples size, and in subsequent data processing. The result show mean of PT,APTT,Platelets count,and Bleeding time is 34.8,39.2,197,6.1 Respectively. There was significant 0.000,0.043,0.004Respectively for PT,APTT,Platelets count There was higher level significant variation in compared with control for PT, Bleeding time 0,006,0.000 Respectively Conclusion: it found that hemostatic mechanism was affected due to renal failure disease.