Abstract:
This is an analytical case-control study, conducted at Khartoum north Teaching
Hospital during the period from January to June 2010. The aim of this study
was Evaluation of some haemostatic parameters (platelet count, PT ,APTTand
INR) in heart disease patients attended Khartoum north Teaching Hospital.
Sixty patients with heart disease were informed about the study and agreed for
participation. The study population was divided into three groups according to
type of disease, 29 ischemic heart diseases, 19 heart failure, 12 Angina.
Five ml of venous blood was taken2.5ml in EDTA containers and 2.5 ml in tri
sodium citrate containers and investigated for the platelet count, PT, APTT and
INR.
Fully automated haematological analyzer Sysmex was used for platelet count,
and automated coagulometer analysis for PT ,APTT and INR .
All heart disrase patients had mean values of Platelet = 253.000cell/mm 3 normal
compared with control value = 265.000 cell/mm3, PT=17.06second, prolong
compared with control mean value = 14.5 second, P.value = 0.01. INR=1.4,
increased compared with control mean value = 1.2, P.value = 0.007.APTT =
32.5second, normal compared with control mean value = 30.6, P.value = 0.65.
The Reseach conclude that the heart disease affect the prothrombin time.
