Abstract:
Across-sectional study conducted during the period from March to
July 2011, aimed to asses the plasma levels of urate and magnesium
in Sudanese with type 1 diabetes. This study includes 75 samples
collected from 45 diabetic patients as a test group and 30 apparently
healthy (non diabetics) as controls. This study was done in
Omdurman hospital. Age and sex of the test group were matched with
the control group. The magnesium and urate levels were measured
using a spectrophotometer and reagent from Biosystem Company
.The data was analyzed using SPSS computer program. The Results
showed a significant reduction in the mean of the plasma levels of
magnesium of the diabetic group when compared with the control
group (p<o.o5). Also showed a significant increase in the mean of the
plasma levels of urate of the diabetes group when compared with that
of the control group .There is a weak positive correlation between the
duration of diabetes and the plasma levels of urate and negative
correlation between the duration plasma levels of magnesium, and
there is a weak positive correlation between the plasma levels of
urate and magnesium.
In conclusion:
The plasma levels of magnesium are reduced in diabetic patients with
type 1 where as that of urate are raised. The plasma levels of
magnesium have negative correlation with the duration of diabetes,
where as the plasma levels of urate have a positive correlation with
the duration of disease.
