Abstract:
This is a screening study carried out in University of Sudan Faculty of
Medical Laboratory Sciences Histopathology and Cytology department,
during the period from April to August 2011. To assess the
Cytomorphological pattern of urine deposit among cigarette smokers, using
conventional cytological stain Papanicolaou stain. 150 individuals
participated in the study, 100 were cigarette smokers, and 50 individual were
non smoker, the duration of smoking was variable and the numbers of
cigarettes smoked per day was also variable, individual with history of
urinary tract infections were excluded from the study,. Smear were prepared,
fixed in 95% Ethyl alcohol and stained with Papanicolaou stain then
examined under the microscope. The cytological assessment reveals the
following: 128 (85.3%) normal, 18 (12%) inflammatory changes and 4
(2.7%) reported with a typical changes, the association between age group
and cytological results in age group ranged from 46 to 55years 9(6%) cases
inflammatory changes with p value 0.000 sig, while association between
duration of smoking per years and cytological result, smokes for 21 to
26years 10(10%) inflammatory changes and 2(2%) a typical changes with p
value 0.000 significant, and number of cigarettes smoking per day for
cytological result 7(7%) inflammatory changes and 3(3%) a typical changes
with p value 0.000 sig. On the basis of this study and review of literature we
conclude that: Cigarettes smoking is one of risk factor of inflammatory and
atypical changes that can be studied using urine cytology, atypical
Cytomorphological changed is associated with older age, longer duration
and large number of cigarettes smoking per day.