Abstract:
A hospital-based analytical descriptive study was conducted in Mohammed Salih
Idress center from March 2011 to June 2011, to determine the morphological and
physiological patterns of anemia among Sudanese patients with Gastro intestinal
bleeding
Hundred Gastro intestinal patients were those who fulfilled the clinical diagnosis
of Gastro intestinal bleeding of both gender , from different region of Sudan and
different tribe ,were informed about the study expected out come and agreement of
participation was obtained. The controls were normal not receive any treatment or
transfusion in their life. A structured questionnaire was used to collect information
about patients age, gender, tribe, blood vomiting, passing of black stool, history of
bilharziasis ,
present of splenomegaly and hepatomegaly, and laboratory
investigations. Blood sample were collected from all patients and controls for use
in laboratory investigation. Statistical package for social science (SPSS version
11.5) computer software was used for data analysis.
The results showed significant difference between the mean level of patients and
control in the following parameters haemoglobin level, hematocrite, RBCs count,
TWBCs, platelet count and RBCs indices (p. value< 0.05).
The study explained that the patterns of peripheral blood picture among study
group 46(46%) were normocytic normochromic type and consider to be highest
prevalence morphological type of anemia among Gastro intestinal patient, 30(30%)
were microcytic hypochromic comes in second class and 24(24%) were dimorphic
picture.
Reticulocytes was significantly increase in compared to control group (p.value
<0.05)
The result showed significantly decrease in the mean level of haemoglobin ,
hematocrite, RBCs count, platelet count and RBCs indices among Chronic and
acute gastro intestinal bleeding patients compared to control group(p.value <0.05)
The results showed insignificant difference between Mean Cell volume,Mean cell
haemoglobin and
Mean cell haemoglobin concentration.in patients with
normocytic normochromic RBCs and control group(p.value>0.05),while they
showed significantly decreased in patient with microcytic hypochromic RBCs and
with dimorphic picture (p.value < 0.05).
