Abstract:
The aim of this research to study renal functions test in Sudanese patients with systemic
lupus erythromatosus )SLE). In addition of estimated creatinine clearance and compared
between the SLE disease and duration of disease . Thirty Sudanese patient samples with
SLE , were selected from different hospital ,from the period February to May 201.Also
thirty healthy people as control.
Venous blood samples (3ml) were taken from all subjects to determine S.creatinie &
B.urea were measured by enzymatic method .S. sodium &S. potassium were measured
by Cornley-Electrolyte analyzer . Creatinine clearance calculated by Cockcroft-Gault
formula.
The study results showed SLE more common in females than males, the ratio was
6:1. The evaluation of the blood urea p=(0.000), creatinine clearance p=(0.004), and body
surface area p=(0.015) were significantly affected in SLE patients ,serum creatinine
p=(0.09), serum sodium p=(0.029) and serum potassium p=(0.14) were insignificantly
not affected in SLE patients compared with control group. Rheumatoid arthritis and
hypertension were present in almost patients . Some patients had renal failure due to
severe complication of the diseases.
