Abstract:
This is a retrospective descriptive study was conducted in Radiation and
Isotope Center Khartoum (RICK), during the period from June 2010 to July
2011. This study aimed to identify the virus Epstein Bar virus in patients
with nasopharyngeal carcinoma who attended the RICK. Epstein Bar virus
was verified in 100 patients between the ages of 14 and 77 years old. 56% of
the patients were male and 44% were female. All specimens were stained
using avidin biotin for immunohistochemistry, periodic acid Schiff’s and
Macchiavillos stains to identify EBV and compare the results to detect the
percent of EPV among patients with nasopharyngeal carcinoma. The percent
of the virus was found 34%,48% and 69% by PAS , Macchiavillos and
avidin biotin respectively .The study was found avidin biotin more efficient
when compared with other methods for detection of Epstein Bar virus
because its more Specific and sensitive method.
The study found that this type of cancer has high rate among males than
in females. Finally, the published scientific data continues to suggest that
infection with Epstein Bar plays an important role in the development of
cancer of the nasopharyngeal carcinoma is likely that associated with other
risk factors.
The study recommended more surveys for the work of communities of
patients using the most advanced molecular techniques to confirm the role of
the Epstein Bar virus in the development of nasopharyngeal cancer in the
Sudan.
