Abstract:
Introduction: There is strong epidemiologic evidence linking Schistosoma
haematobium infection with carcinoma of the bladder. The cytological screening
for urinary tract cancer is not fully evaluated in Sudan. Objectives: The aim of
this study is to demonstrate the Cytomorphological changes among Sudanese
patients with urinary Schistosomiasis in Khartoum city. Material and methods:
Cross sectional hospital base study, Sample collected from Khartoum North
Teaching Hospital, its processing and preparation was done at University of
Sudan Faculty of Medical Laboratory Sciences, post graduate research
laboratory. Two hundred patients, with confirmed diagnosis of urinary
Schistosomiasis approached. Full voided urine was collected in sterile container;
cytological smear was prepared from sediment and stain with Pap stain. Results:
the majority of patient their age less than 20 year.Ova detected in 69(34.5%) of
patient samples, the cytological finding among this group was that 67 (33.5%)
were normal, and two (1.0%) cases reported as atypical. While the rest of urine
sample 131 (65.5%) were negative for bilharzias ova and atypia. Discussion:
The outcome of this study is in agreement and in consistence with previous
works and literature performed In Egypt, Kenya and West Africa. It disagrees
with some studies due to difference in method of investigation and study groups.
Recommendation: Parents should look after their children and advise them not
to swim or urinate in irrigation canals. Further studies are needed to address this
topic with large sample size. Future study may investigate patient with different
types of bladder cancer in histopathological sections, and screen the presence of
Schistosoma infection.
